Centromere location changes when specific proteins are knocked out (IMAGE)

University of Washington

Centromere location changes when specific proteins are knocked out

Caption

UW researchers used fluorescence microscopy to study the mechanism behind how and why centromeres (labeled in blue with white arrow) normally localize to the top of the nucleus (dark circle). Shown here are two neural stem cells (white circles). The cell on the right is missing a key protein involved in centromere organization so the centromeres are not at the top of the nucleus. The scale bar on the bottom right is 5 micrometers long.

Credit

Taylor and Cabernard/JCB

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