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Higher Education Press

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VDR signaling enables subcutaneous adipogenesis by upregulating ZNF423, adipogenesis activators while downregulating adipogenesis inhibitors. VDR deficiency drives SAT decline in Vdr-/- or HGPS or aged mice. Calcipotriol treatment can counteract VDR deficiency and rescue SAT loss in HGPS mice.

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HIGHER EDUCATION PRESS

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