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Caption
High-resolution structures of KCC4 in different ion conditions. A 3D reconstruction of KCC4KNO3 colored by local resolution. B Sample of EM maps at transmembrane helices 1 (TM1) and 6 (TM6) of KCC4 in different ion conditions at the contour level of 4 σ. C Cartoon representation of one KCC4KCl subunit (left) and the zoom-in view of three potential ion binding sites S1–S3 (right). S1–S3 are equivalent to the three sites (SK, SCl1, SCl2) that we initially assigned in the KCC16KKR structure. The ions are shown as cyan spheres
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HIGHER EDUCATION PRESS
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