'mini-brain' (IMAGE)

National Yang Ming Chiao Tung University

'mini-brain'

Caption

A “mini-brain” grown from human stem cells for 76 days, engineered so that cells making DACH1 glow green. Red marks brain stem cells and cyan marks dividing cells. The flower-shaped clusters mimic the stem-cell zone of the developing human brain, and dividing stem cells carrying DACH1 appear both inside and outside these clusters.

 

DACH1:GFP (green)

Cortical progenitor marker PAX6 (red)

Proliferative marker pH3 (cyan)

Nuclei (blue)

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The authors

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