Spatiotemporal modulation to encode nerve fluorescence (IMAGE)

SPIE--International Society for Optics and Photonics

Spatiotemporal modulation to encode nerve fluorescence

Caption

Fluorescence-guided surgery can make nerves easier to distinguish from surrounding tissue, but bright ambient lighting can overwhelm the weak fluorescence signals, disrupting imaging and surgical workflow. A newly developed system uses spatiotemporal modulation to encode nerve fluorescence with a distinctive spatial and temporal pattern, allowing it to be separated from background illumination.

Credit

Y. Zhao (Physical Sciences Inc.)

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