Antioxidant Protein, Decreased by Obesity, Promotes Egg Cell Maturation (IMAGE)
Caption
Researchers studying infertility in obese female mice found dramatically lower levels of a protein called TIGAR, which controls redox metabolism. When they reduced TIGAR levels from healthy oocytes by RNA interference (shown above), many cells showed disruptions in meiosis, either dividing symmetrically instead of asymmetrically (pink stars) or failing to divide (blue arrows).
Credit
Wang et al.
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