Remodelin to the Rescue of Nuclear Defects? (3 of 3) (VIDEO)

American Association for the Advancement of Science (AAAS)

Caption

Live imaging shows nuclear shape rescue in cells depleted for Lamin A/C upon treatment with the small molecule Remodelin (time frame: 1 picture / 15min). This video relates to a paper that appeared in 2 May, 2014, issue of Science, published by AAAS. The paper, by Delphine Larrieu at the Wellcome Trust/Cancer Research UK (CRUK) Gurdon Institute in Cambridge, UK, and colleagues was titled, "Chemical Inhibition of NAT10 Corrects Defects of Laminopathic Cells."

Credit

[Video courtesy of Delphine Larrieu]

Usage Restrictions

Please cite the owner of the video when publishing. This video may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact <i>Science</i> for permission.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.