The M. Tuberculosis Sliding Clamp (DnaN) in Complex with (Cyclohexyl-)Griselimycin (IMAGE)

Helmholtz Centre for Infection Research

The M. Tuberculosis Sliding Clamp (DnaN) in Complex with (Cyclohexyl-)Griselimycin

Caption

The protein forms a homodimeric ring (shown as blue cartoon & surface representation). Each polypetide chain binds one molecule of griselimycin (red). The optimized compound cyclohexylgriselimycin contains an additional cyclohexane moiety (yellow, shown only for the ligand in the foreground).

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HZI/Lukat

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