Three microseconds from the life of a nucleosome (IMAGE)

Hubrecht Institute

Three microseconds from the life of a nucleosome

Caption

The image shows three microseconds from the life time of a nucleosome. Snapshots in time were taken every 4 nanoseconds and were superimposed on the core region of the histones (white). The positions of the DNA and the flexible histone tails in all snapshots are shown The DNA is in yellow and the histone tails in blue, green, red, orange and cyan. The ample motion of the DNA arms is known as nucleosome breathing motion. Remarkably, in this nucleosome, the lower arm moves more than the upper one due to the DNA sequence.

Credit

Credit: Jan Huertas and Vlad Cojocaru, ©MPI Münster, ©Hubrecht Institute.

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