Restoring Nerve Insulation (IMAGE)

Cincinnati Children's Hospital Medical Center

Restoring Nerve Insulation

Caption

This image from a paper in Nature Medicine shows how inhibiting an enzyme called HDAC3 in mice increases the expansion of Schwann cells (green). Schwann cells form a protective insulating layer called the myelin sheath around the nerves. Blocking HDAC3 increases the production of myelin proteins, shown in red. Scientists from Cincinnati Children's tested an experimental molecular therapy in mice that restored nerve insulation and improved limb function following nerve injury.

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Cincinnati Children's

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