ABS Pairing Induces a Significant Decrease in Fear Response (VIDEO)
Caption
In the conventional fear reduction procedure (top), the CS group are subjected to the anxiety-producing sound without electric shocks. Since a freezing response decreases at a slow rate, mice exhibited extreme freezing responses both at the first (a) and second (b) auditory stimulations. In the ABS pairing (bottom), moving LED light was presented with the second auditory stimulation. While an extreme freezing response was also seen in mice at the first auditory stimulation (c), the pairing auditory stimulation with moving light (d) induced a significant decrease in mice's freezing response.
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