Fluorescent Proteins (mCherry) Linked To The Newly Developed Optogenetic Tool CRY2clust Quickly Clus (VIDEO)

Institute for Basic Science

Caption

mCherry tends to form only little or no clusters when used in combination with the traditional version of CRY2 (CRY2PHR), but when attached to CRY2clust (CRY2PHR-A9) a lot of clusters form rapidly. The video shows the effect of a single pulse of light shone on the cell at the one minute mark (01:00). The fluorescent protein clusters form rapidly and then disassemble. This tool can be applied to study and control specific biological phenomena happening in the cytoplasm, in the nucleus, and on the cellular membrane.

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