CD Lymph Node (IMAGE) University of Pennsylvania School of Medicine Caption This is an example of lymph node tissue from a person with, idiopathic multicentric Castleman disease. Image shows Increased number of blood vessels and smaller germinal centers where immune cells mature in the lymph node, which are two of the pathology features needed to make the diagnosis. Credit David Fajgenbaum, MD, Perelman School of Medicine, University of Pennsylvania Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.