Illustration of in-cell RIDME Distance Determination (IMAGE)

University of Konstanz

Illustration of in-cell RIDME Distance Determination

Caption

In-cell distance determination by EPR reveals essential structural information about biomacromolecules under native conditions. For the first time, the pulsed EPR technique RIDME (relaxation induced dipolar modulation enhancement) was utilized for distance measurements inside cells. It provides a five-times improved sensitivity as compared to the previously used double electron-electron resonance approach.

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Research group Professor Malte Drescher, University of Konstanz

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