Even Bacteria Have Baggage (IMAGE)

PLOS

Even Bacteria Have Baggage

Caption

Yen and Papin showed cases where adaptation to one drug, followed by adaptation to a different drug, led to different final resistance levels of the two drugs compared to adaptation to the two drugs in the opposite order. Drug history-dependent effects in the adapted populations of bacteria led to observable differences both genetically (e.g., mutations) as well as phenotypically (e.g., resistance levels and pigment production).

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Phillip Yen

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