Immune Cells Promote or Prevent Cytomegalovirus Activity in Mice Depending on Location in the Body (IMAGE)

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Immune Cells Promote or Prevent Cytomegalovirus Activity in Mice Depending on Location in the Body

Caption

Treg have divergent control of MCMV infection depending upon the issue. In the spleen, Treg antagonize CD8+ effector function and promote viral persistence while in the salivary gland Treg prevent IL-10 production from Foxp3 - CD4+ T cells and limit viral reactivation and replication.

Credit

Almana, et al. (2017)

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