Phosphorylated Tyrosine Hydroxylase Increases in IRBIT KO Mice (IMAGE)

RIKEN

Phosphorylated Tyrosine Hydroxylase Increases in IRBIT KO Mice

Caption

Analysis showed that IRBIT knockout (KO) mice (right) had significantly more phosphorylated tyrosine hydroxylase than wild type control mice (left). This led to abnormally high levels of dopamine and characteristic hyperactivity and social abnormalities. Bottom panels are magnified imaged of the regions bounded by white rectangles in the upper panels.

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RIKEN

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