Conceptual Diagram (IMAGE)
Caption
This is a Conceptual Diagram on the Entanglement of Toxic Protein and Foxo Protein Coiled-coil Structure; In a nerve cell, the coiled-coil structure of polyglutamine toxic protein is entangled with Foxo protein, a transcription factor. Here, the Foxo protein loses its normal functions and early neuropathology of degenerative brain disorder such as dendrite loss appears.
Credit
Daegu Gyeongbuk Institute of Science and Technology (DGIST)
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