Identification of Cancer Status for More Than 50 Cancer Types, as Well as Tissue of Origin Localizat (IMAGE)

Dana-Farber Cancer Institute

Identification of Cancer Status for More Than 50 Cancer Types, as Well as Tissue of Origin Localizat

Caption

Cell-free DNA is isolated from blood samples drawn from a patient without cancer (top) or with cancer (bottom), and subjected to a targeted methylation sequencing assay. Sequencing results identifying methylated (red) or unmethylated (blue) CpG regions are fed into a machine-learning classifier that can identify the presence or absence of cancer, as well as identify the tissue of origin (TOO).

Credit

Editorial Figure by Allen McCrodden, Associate Director, Creative Group of ProEd Communications

Usage Restrictions

Editorial Figure by Allen McCrodden, Associate Director, Creative Group of ProEd Communications

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.