Rebellious Microbiota Contribute to Skin Damage in Some Cancer Treatments (3 of 4) (IMAGE)

American Association for the Advancement of Science (AAAS)

Rebellious Microbiota Contribute to Skin Damage in Some Cancer Treatments (3 of 4)

Caption

It's not rocket science: deciphering the adverse events during modern cancer treatment. Novel hair eruption inflicts strong inflammation during targeted anti-cancer therapy. An otherwise strictly organized process is disrupted during cancer treatment thereby hampering its efficiency. Like the start of a subsurface missile, without EGFR/ERK signaling an erupting hair leaves a strong inflammatory footprint in the skin and, aggravated by microbes, on its surface. This material relates to a paper that appeared in the Dec. 11, 2019, issue of Science Translational Medicine, published by AAAS. The paper, by J. Klufa at Medical University of Vienna and Comprehensive Cancer Center in Vienna, Austria; and colleagues was titled, "Hair Eruption Initiates and Commensal Skin Microbiota Aggravate Adverse Events of anti-EGFR Therapy."

Credit

[Credit: Jörg Klufa and Thomas Bauer]

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