CRISPR interference (IMAGE) Max-Planck-Gesellschaft Caption CRISPR interference uses a deactivated Cas9 protein (dCas9) and a single guide RNA (sgRNA) and enables specific knockdowns of enzymes in the metabolic network of bacteria. Deep sequencing can track growth of 7177 CRISPRi in parallel and informs about robustness of each CRISPRi strain. Credit Max Planck Institute for terrestrial Microbiology/Link Usage Restrictions Use of images is limited to editorial coverage of scientific topics relating to the activities of the Max Planck Society. Any kind of commercial use (including, in particular, the exploitation of images by means of sale or incorporation in image databases or image catalogues) as well as any promotional use/use for merchandise purposes, disclosure to third parties or granting of related rights to third parties is expressly not permitted. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.