Prasanth, Tripathi, Song, University of Illinois at Urbana-Champaign (IMAGE)

University of Illinois at Urbana-Champaign, News Bureau

Prasanth, Tripathi, Song, University of Illinois at Urbana-Champaign

Caption

Cell and developmental biology professor Kannanganattu Prasanth (left), post-doctoral researcher Vidisha Tripathi (seated), undergraduate research assistant David Song and their colleagues found that a long non-coding RNA, MALAT1, plays a key role in pre-mRNA processing. Aberrant regulation of the MALAT1 gene is associated with several cancers, as are some of the splicing factors it regulates. Similarly, some of the genes whose pre-mRNA splicing is regulated by MALAT1 are cancer "signature genes."

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L. Brian Stauffer, U. of I. News Bureau.

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