Figure: Biotransformation of pX into TPA by Engineered <em>E. coli</em> (IMAGE)

The Korea Advanced Institute of Science and Technology (KAIST)

Figure: Biotransformation of pX into TPA by Engineered <em>E. coli</em>

Caption

This schematic diagram shows the overall conceptualization of how metabolically engineered E. coli produced TPA from pX. The engineered E. coli was developed through reconstituting a synthetic metabolic pathway for pX conversion to TPA and optimized for increased TPA yield and byproduct elimination. Two-phase partitioning fermentation system was developed for demonstrating the feasibility of large-scale production of TPA from pX using the engineered E. coli strains, where pX was supplied in the organic phase and TPA was produced in the aqueous phase.

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KAIST

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