Interaction Between HIV-1 and Antibodies Modeled with New Mathematical Precision (IMAGE)
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In this work, the authors experimentally determined or collected from the literature parameters that quantitatively define the interaction between Human Immundeficiency Virus 1 (HIV-1) virions and neutralizing antibodies (nAbs) and between HIV-1 virions and the human host during viral transmission. These parameters were subsequently utilized to mathematically model HIV-1 transmission and antibody neutralization, yielding predictions of person-to-person HIV-1 transmission probabilities and the potential protective effects of neutralizing antibodies.
Credit
Oliver Brandenberg
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