Adenosine Receptor Antagonists' Effect on Mouse Brain Development (1 of 1) (VIDEO)

American Association for the Advancement of Science (AAAS)

Caption

This video illustrates effects of caffeine on the migration of neurons in mice. When caffeine binds to A2A receptors, the migration speed of these neurons is decreased (as shown on the right). The cells therefore reach their intended destination later than planned. This video relates to a paper that appeared in the Aug. 7, 2013, issue of Science Translational Medicine, published by AAAS. The paper, by C.G. Silva at INSERM in Marseille, France, and colleagues was titled, "Adenosine Receptor Antagonists Including Caffeine Alter Fetal Brain Development in Mice."

Credit

Video courtesy of INSERM / Christine Métin - Christophe Bernard

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