Protease-Protein Brush (IMAGE)

University of California - Berkeley

Protease-Protein Brush

Caption

The height of the new protein brush, made from the neurofilament-derived proteins, can be precisely controlled with protein-digesting enzymes, or proteases. The protease thrombin, shown at the top, cut the brush superficially at the red cross marks, resulting in a negligible change to the height of the brush. The protease clostripain cut the brush much more deeply at the yellow cross marks and thus had a more measurable effect on height.

Credit

Schematic by Sanjay Kumar

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