Putting a Finger on Plant Stress Response (IMAGE)
Caption
Researchers from the University of Tsukuba have found that a PHD zinc finger-like domain in SUMO E3 ligase SIZ1 is essential for protein function in Arabidopsis. Deletion or mutation of the domain failed to complement a siz1 mutant, confirming its role in sumoylation. They also showed that the finger recognizes tri-methylated histone proteins, suggesting a role for the finger domain in SIZ1/SUMO-mediated transcriptional regulation of stress response-associated genes.
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University of Tsukuba
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