Gene Therapy to Treat Blindness: Finding the Right Dose (3 of 4) (IMAGE)

American Association for the Advancement of Science (AAAS)

Gene Therapy to Treat Blindness: Finding the Right Dose (3 of 4)

Caption

Green fluorescent protein in macular photoreceptors after subretinal injection of AAV8 in a monkey retina. Cell nuclei are labeled blue and cone photoreceptors are labeled red. GFP-positive RPE cells are adjacent to the photoreceptor outer segments. This image relates to a paper that appeared in the June 22, 2011, issue of Science Translational Medicine, published by AAAS. The paper, by Dr. Luk Vandenberghe of the University of Pennsylvania in Philadelphia and colleagues, was titled, "Dosage Thresholds for AAV2 and AAV8 Photoreceptor Gene Therapy in Monkey."

Credit

Image courtesy of Luk H. Vandenberghe

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