CRISPR-sciATAC (IMAGE)

New York Genome Center

CRISPR-sciATAC

Caption

CRISPR-sciATAC is a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide. The new method harnesses the programmability of the gene editing system CRISPR to knock-out nearly all chromatin-related genes in parallel, offering researchers deeper insights into the role of DNA accessibility in cancer and in rare diseases involving chromatin.

Credit

Sanjana Lab of New York Genome Center and NYU

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