Aurura A in PKD Cysts (IMAGE)

Rockefeller University Press

Aurura A in PKD Cysts

Caption

Red staining indicates the presence of activated Aurora A kinase in the epithelial cells lining cysts in the kidneys of patients with polycystic kidney disease (PKD). A new study in The Journal of Cell Biology suggests that Aurora A may contribute to PKD, a common genetic disease, by inactivating a key calcium channel in kidney cells.

Credit

Plotnikova, O.V., and E.A. Golemis. 2011. J. Cell Biol. doi:10.1083/jcb.201012061.

Usage Restrictions

Reporters may freely use these materials in news coverage, with the appropriate credit information.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.