STIM1 Protein Strikes a Vital Balance in Vertebrates (IMAGE)

American Association for the Advancement of Science (AAAS)

STIM1 Protein Strikes a Vital Balance in Vertebrates

Caption

STIM-ulating Orai1 and un-STIM-ulating Cav1.2. This diagram illustrates how STIM1 in the ER membrane activates Orai1 (green subunits) and inhibits Cav1.2 (brown subunits) in the plasma membrane (PM). Please see the Perspective for the complete caption. This image relates to a Perspective that appeared in the October 1, 2010, issue of Science, published by AAAS. The Perspective, by Dr. Michael D. Cahalan of the University of California, Irvine in Irvine, Calif., was titled, "A Stimulating Look At Calcium Channels.”

Credit

Image: Science © 2010 AAAS

Usage Restrictions

Please cite the owner of the image when publishing. This image may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact <i>Science</I> for permission.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.