When Gene Silencing Fails (IMAGE)

European Molecular Biology Laboratory

When Gene Silencing Fails

Caption

These microscopy images show the region of the embryo larva that will develop into the adult fruit fly's wing. In cells genetically manipulated so that PR-DUB cannot remove the gene-silencing tag (left), a gene which would normally be silenced becomes turned on (red) -- a situation which is corrected when PR-DUB's activity is restored (right).

Credit

J. Mueller/EMBL

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