An Unexpected Link (IMAGE)

Rockefeller University

An Unexpected Link

Caption

Researchers found abnormal calcium deposits, a feature of certain autoinflammatory diseases, in the brains of all six patients (P1 to P6) lacking the immune protein ISG15. The deposits appear as white spots in scans from two patients. These do not appear in the scan from the healthy mother of the P4, P5 and P6 (ISG151-/+).

Credit

Hacettepe University Children's Hospital, Turkey; National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Iran; Central South University, China/<i>Nature</i>

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