Unsumoylated vs. Sumoylated Alpha-Synuclein (IMAGE)

Rockefeller University Press

Unsumoylated vs. Sumoylated Alpha-Synuclein

Caption

Unsumoylated alpha-synuclein aggregates into fibrils (right), whereas sumoylated alpha-synuclein doesn't (left). New research in the Journal of Cell Biology suggests that sumoylation might prevent the protein aggregations that typify Parkinson’s disease.

Credit

Krumova, P., et al. 2011. J. Cell Biol. doi:10.1083/jcb.201010117.

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