Disease Progression in Spinal Interneurons in Normal ALS Vs. Autophagy-Suppressed ALS Models (IMAGE)

The Zuckerman Institute at Columbia University

Disease Progression in Spinal Interneurons in Normal ALS Vs. Autophagy-Suppressed ALS Models

Caption

These are differences in disease progression in spinal interneurons, a type of nerve cell that generally succumbs to ALS in later stages of disease. Left: Normal ALS models, showing protein aggregation (red/green) in spinal interneurons. Right: autophagy-suppressed ALS models, showing virtually no aggregation.

Credit

Tom Maniatis/Columbia University's Zuckerman Institute

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