Effect of ATF6 Gene Therapy on Mouse Myocytes (IMAGE)

San Diego State University

Effect of ATF6 Gene Therapy on Mouse Myocytes

Caption

ATF6 is protective in the heart; it is expressed at high levels in the young heart, and low levels in the aged heart. Gene therapy studies that were done in the Glembotski lab at the SDSU Heart Institute have shown that restoring ATF6 in the aged mouse heart to levels in the young heart provides remarkable protection against heart disease, and could pave the way for development of this therapy for use in humans in the near future.

Credit

Chris Glembotski

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