Difference In Nuclear Size Of Normal And Mutant LEM2-Deficient Cells When Treated With Cerulenin (IMAGE)

Hiroshima University

Difference In Nuclear Size Of Normal And Mutant LEM2-Deficient Cells When Treated With Cerulenin

Caption

The nucleus (green) of cells (magenta) with and without LEM2 (WT and lem2?) reacting to a compound that inhibits membrane synthesis, called cerulenin. The cells without LEM2 shrink 105 minutes after the addition of cerulenin while the nucleus of the WT cells does not, showing that Lem2 is involved in maintenance of an appropriate nuclear size.

Credit

From the paper: Nuclear membrane protein Lem2 regulates nuclear size through membrane flow

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