Neural Stem Cell Therapy for Rare Brain Disorders (IMAGE)

American Association for the Advancement of Science (AAAS)

Neural Stem Cell Therapy for Rare Brain Disorders

Caption

The image illustrates direct injection of human neural stem cells (HuCNS-Sc) into the brain's white matter, which is composed of bundles of nerve axons. There is lack of myelin, an insulating coating, in Pelizaeus-Merzbacher disease (PMD), a severe condition that affects male children. Over time some stem cells become myelinating oligodendrocytes. This image relates to a paper that appeared in the October 10, 2012, issue of Science Translational Medicine, published by AAAS. The paper, by N. Gupta at University of California, San Francisco in San Francisco, Calif., and colleagues was titled, “Neural Stem Cell Engraftment and Myelination in the Human Brain.”

Credit

Illustration by Kenneth Probst

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