Getting to the Nucleus of Acute Kidney Injury (1 of 1) (IMAGE)

American Association for the Advancement of Science (AAAS)

Getting to the Nucleus of Acute Kidney Injury (1 of 1)

Caption

The compound PCN helped reduce injury to kidney cells in a rat model of induced kidney injury (I/R). This material relates to a paper that appeared in the May. 13, 2020, issue of Science Translational Medicine, published by AAAS. The paper, by X. Yu at Children's Hospital of Nanjing Medical University in Nanjing, China; and colleagues was titled, "Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI."

Credit

[Credit: X. Yu <i>et al., Science Translational Medicine</i> (2020)]

Usage Restrictions

Please cite the owner of the material when publishing. This material may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact <i>Science</i> for permission.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.