Collagen-Binding Antibodies Treat Rheumatoid Arthritis and Pulmonary Fibrosis in Mice (1 of 1) (IMAGE)

American Association for the Advancement of Science (AAAS)

Collagen-Binding Antibodies Treat Rheumatoid Arthritis and Pulmonary Fibrosis in Mice (1 of 1)

Caption

We have taken a simple translational approach to improve anti-inflammatory antibodies in animal disease models by conferring collagen binding affinity to the antibodies. This material relates to a paper that appeared in the November 6th, 2019, issue of Science Advances, published by AAAS. The paper, by K. Katsumata at University of Chicago in Chicago, IL, and colleagues was titled, "Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies."

Credit

[Credit: Kiyomitsu Katsumata (kiyomitsu.katsumata@astellas.com)]

Usage Restrictions

Please cite the owner of the material when publishing. This material may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact <i>Science</i> for permission.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.