Regulated Lysosomal Exocytosis Mediates Cancer Progression (1 of 2) (IMAGE)

American Association for the Advancement of Science (AAAS)

Regulated Lysosomal Exocytosis Mediates Cancer Progression (1 of 2)

Caption

The picture gives a graphical rendering of a cancer cell that up-regulates the process of lysosomal exocytosis to effectively degrade the extracellular matrix (ECM) and transition to a more invasive/migratory and drug resistant state. This material relates to a paper that appeared in the Dec. 18, 2015, issue of Science, published by AAAS. The paper, by E. Machado at St. Jude Children's Research Hospital in Memphis, Tenn., and colleagues was titled, "Regulated lysosomal exocytosis mediates cancer progression."

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[Credit: Alessandra d'Azzo]

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