APC Triggers Actin Assembly (IMAGE)

Rockefeller University Press

APC Triggers Actin Assembly

Caption

A new study in the Journal of Cell Biology suggests that APC mutations could promote tumors not just through their effects on Wnt signaling, but also through their impact on the cytoskeleton. This image of a layer of cells highlights the actin structures that formed in one cell after an injection of an APC fragment. The inset reveals that the GFP-tagged fragment latched onto actin.

Credit

Okada, K., et al 2010. J. Cell Biol. doi:10.1083/jcb.201001016.

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