A Synthetic Molecular Code Called Bi-PIP (IMAGE)

Kyoto University

A Synthetic Molecular Code Called Bi-PIP

Caption

A synthetic molecular code called 'Bi-PIP' has been designed that includes an inhibitor of an epigenetic reader bromodomain and selective DNA-binding pyrrole-imidazole polyamides. The Bi-PIP scripted a biomimetic epigenetic code emulating the natural histone acetylation process over a target nucleosome and switched 'ON' precise genes inside living cells.

Credit

SaiPadma Priya

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