Architecture of HIV-1 CA Hexameric Cavity (IMAGE)

University of Texas at Austin, Texas Advanced Computing Center

Architecture of HIV-1 CA Hexameric Cavity

Caption

The HIV-1 virus has evolved a way to import into its core the nucleotides it needs to fuel DNA synthesis, according to research led by Juan R. Perilla at the University of Delaware. Using the TACC Stampede2 and PSC Bridges supercomputers, Perilla's team has shown for the first time that a virus performs an activity such as recruiting small molecules from a cellular environment into its core to conduct a process beneficial for its life cycle.

Credit

Xu, et al.

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