The New Nanosheet Process (IMAGE)

Goethe University Frankfurt

The New Nanosheet Process

Caption

The protein complex to be examined (yellow) is attached to the smart nanosheet via a nickel complex with the aid of a marker (red chain with pentagons). Unwanted proteins (gray) are repelled by the hydrogel (black grid). After freezing the entire structure, including a thin film of water, this can be irradiated with electrons to obtain images of the bound proteins, from which a computer can then calculate the 3D structure of the protein.

Credit

Andrey Turchanin/Zian Tang

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