Taking a Catnap? Mouse Mutation Shown to Increase Need for Sleep (IMAGE)

University of Tsukuba

Taking a Catnap? Mouse Mutation Shown to Increase Need for Sleep

Caption

Figure. A single phosphorylation site, S551 of SIK3 regulates daily sleep amounts and sleep need in mice. The mutations at S551 alter the interaction of SIK3 with PKA and 14-3-3, which leads to the increased non-REM sleep amounts and sleep need in Sleepy, S551A, and S551D mutant mice.

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University of Tsukuba

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