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Recent reports showed that stem cells transplantation was effective on improving brain injury from severe intraventricular hemorrhage in newborn rats. As a next step, because stem cells secrete bioactive extracellular vesicles, researchers tried to prove the therapeutic effects of EVs as next-generation therapeutic candidates against newborn IVH. Intracerebroventricular transplantation of EVs secreted from stem cells effectively attenuated brain injury from severe IVH via transferring brain-derived neurotrophic factor in newborn rats.
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AlphaMed Press
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