Graphical Abstract (IMAGE) AlphaMed Press Caption Recent reports showed that stem cells transplantation was effective on improving brain injury from severe intraventricular hemorrhage in newborn rats. As a next step, because stem cells secrete bioactive extracellular vesicles, researchers tried to prove the therapeutic effects of EVs as next-generation therapeutic candidates against newborn IVH. Intracerebroventricular transplantation of EVs secreted from stem cells effectively attenuated brain injury from severe IVH via transferring brain-derived neurotrophic factor in newborn rats. Credit AlphaMed Press Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.