Modified Monoxygenase (IMAGE)

Max-Planck-Gesellschaft

Modified Monoxygenase

Caption

An enzyme becomes more versatile: With the help of genetic modifications, Max Planck chemists have altered this monoxygenase in such a way that it converts numerous substrates. Two domains (blue and yellow) are drawn together through the substitution of two amino acids (left, red dots) with the result that the remote binding pocket enlarges due to an induced allosteric effect (right, white).

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Image: MPI for Coal Research

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