diagram (IMAGE)

The Chinese University of Hong Kong

diagram

Caption

Under normal situation (image on the left), the closely packed choroid plexus restrains molecules in the blood stream from entering the CSF freely; the loss of SOX9 function (image on the right) resulted in the loss of collagen IX, eventually losing its protection against the entry of unwanted or harmful substance to the brain passing into the CSF.

Credit

CUHK

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