Accumulation of Defective Mitochondria (IMAGE)

Rockefeller University Press

Accumulation of Defective Mitochondria

Caption

Parkin (green) promotes the turnover of damaged mitochondria (red, left), but defective organelles accumulate near the nucleus if Parkin lacks its ubiquitin ligase activity (right).

Credit

Lee, J.-Y., et al. 2010. <i>J. Cell Biol.</i> doi:10.1083/jcb.201001039.

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